According to a report commissioned by the Prevent Blindness America organization, eye disorders and treatment for people with vision loss cost close to $139 billion annually. 3D printing has been called on multiple times to help learn about and diagnose eye disease, as well as to create implants and create corneas for transplant patients, but it’s not used as often to treat them, as it can be very difficult to deliver drugs into a person’s delicate eyes. But a researcher from Washington State University (WSU) has just been awarded a grant from the US Department of Defense to come up with an easier, less expensive and painful way to treat serious eye diseases…using 3D printing.
While eye drops may seem convenient, they’re not always that effective because they can be diluted by tears. A physical barrier exists between most parts of a person’s eye and its blood vessels, so doctors often have to turn to direct eye injections and laser surgery to treat eye disease. Unfortunately, periodic direct eye injections can each cost nearly $2,000, and laser therapy comes with some risky side effects. That’s why it’s so important to use modern technology to find less costly and more efficient ways to deliver ocular drugs.
The DoD gave Kuen-Ren “Roland” Chen, an assistant professor in the WSU School of Mechanical and Materials Engineering, an 18-month, $264K exploratory grant to develop a programmable microneedle array, using 3D printing, that will be able to deliver drugs in a sustained manner directly into a patient’s eye.
Touted as a minimally invasive, pain-free alternative to the standard, scary-looking hypodermic needle and syringe, microneedles are tiny, and can be stacked next to each other in a group to form a microneedle array. Chen, along with WSU PhD student Maher Amer, is working to improve upon existing microneedle technology by developing a locking and unlocking technique for an array of 3D printed microneedles.
Chen’s method locks microneedles in place with a polymer gel, and would give doctors a way to attach the array to a patient’s eye, so necessary drugs can be delivered for long periods of time; later, the microneedle array can be easily detached.
Not only does a steady, sustained delivery of drugs make delivery more efficient, it also lowers the cost by reducing how much of the drug is required for treatment, as well as limit visits to the patient’s clinic or hospital. In addition, Chen said that his 3D printed microneedle array technology will cause fewer side effects and less pain than direct eye injections, and also be far less invasive.
Right now, the researchers are in the middle of developing the necessary mold for fabricating the microneedles, and testing out Chen’s innovative locking mechanism. Chen and Amer have initial plans to develop the microneedle array so that it can deliver drugs directly into the eye for a month. While this sounds like a terrifyingly long amount of time, it could actually lower abnormal blood vessel growth more effectively than using a single direct eye injection.
In the future, the technology could potentially be used to treat major eye diseases, like age-related macular degeneration and diabetic retinopathy.
Discuss this and other 3D printing topics at 3DPrintBoard.com or share your thoughts below.[Source/Images: WSU]
Subscribe to Our Email Newsletter
Stay up-to-date on all the latest news from the 3D printing industry and recieve information and offers from thrid party vendors.
You May Also Like
NASA Funds 3D Printing Research in 2022 SBIR/STTR Awards
Out of 333 proposals that NASA is funding as part of its 2022 Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) program, 24 are either creating new...
House 3D Printing, Bacterial Materials, and More Awarded by 3D Pioneers Challenge
The 3D Pioneers Challenge awards the best and most innovative breakthrough projects in 3D printing. This year, the jury selected projects from around the world across several categories, including medtech,...
200 3D Printed Houses Planned by Alquist 3D and Black Buffalo
Alquist 3D is a Virginia-based additive construction (AC) company, specializing in printing affordable, cement-based residential homes. Earlier this year, we covered a story about Alquist printing the first owner-occupied residential...
World’s Largest Concrete 3D Printing Facility Opened by GE Renewable Energy
The more that the renewable energy and additive manufacturing (AM) sectors evolve, the clearer it becomes how much the two industries have to offer one another. So far, this has...