In the recently published ‘Electrically Conducting Hydrogels for Health care: Concept, Fabrication Methods, and Applications,’ Shweta Agarwala of the Department of Engineering at Aarhus University in Denmark researchers 3D printing techniques in the medical realm, offering a review of conductive hydrogels.
As 3D printing began to infiltrate the mainstream, industries such as automotive, aerospace, and construction have been positively impacted—and now, medical applications have gone beyond 3D models and devices as scientists continue to make huge strides in bioprinting. Scaffolds are a common structure used in tissue engineering featuring a variety of different hydrogels; however, they can also be used for a wide range of applications today, from smart wearables to biosensors, implants, and avenues to wound management.
Hydrogels are attractive for use in research and other applications due to:
- Ideal extracellular matrix (ECM)
- Cell support
- Natural and synthetic hydrophilic polymer chains offering high absorption of water
“Although hydrogels have found niche application in tissue engineering, they are inherently insulating by nature. Recent research has shown that hydrogels not only possess necessary characteristics to support biological species but can also interface with electrical circuitry if modified,” states Agarwala. “Hence, research on conducting hydrogels have gained widespread interest for applications such as health recording electrodes.”
Agarwala notes that in general, the conductivity associated with hydrogels is ionic conductivity.
“The contribution from additives materials to overall conductivity in such cases is small. However, recent research efforts in this direction have shown promise in inducing electrical conductivity from the additive materials,” states Agarwala.
While the method most often used for aqueous compatible conducting materials is to use ultrasonic energy or heating, five other approaches are available:
- Hydrogel monomers with cross-linkers and nanoparticles are gelated together.
- Nanoparticles are physically embedded into the hydrogel matrix after gelation.
- Nanoparticle precursors are loaded into the gel.
- Cross-linking using nanoparticles forms hydrogels.
- Hydrogels are formed using nanoparticles, polymers, and other molecules.
One of the greatest benefits in 3D printing is that users are able to create much more complex geometries, along with enjoying enormous latitude in both design and customization, as well as being able to make projects faster, and make changes to them on demand. All of these benefits apply to why there has been such an increase in 3D printing conducting hydrogels.
Techniques usually rely on shear thinning, causing them to flow as pressure is applied, using a piezoelectric head.
Such hydrogels have the potential to be used in sensor technology, drug delivery systems, and tissue engineering. A variety of composites have been used too, from graphene-chitosan to silica nanoparticles, silica alumina, but the author points out that commercialization of such manufacturing is ‘still far away,’ due to the many challenges involved.
“A piezoelectric material deforms on applying voltage or current. Thus, the orifice opening can be controlled by varying the voltage applied to the printer head. Inkjet printing creates small droplets (sub-micron volume), which are deposited on the surface,” states Agarwala. “Small volume of material deposition, as against large material ejection through extrusion, helps to print high-resolution constructs and scaffolds.
“Ink development is considered one of the most important aspects of 3D printing. Hydrogel inks need to have the right rheological properties to fulfill the physical and mechanical needs of the orienting process.”
“These materials are unable to follow the original design models, as the printed construct does not retain the original shape. Achieving functional gradients and hierarchical properties have also been challenging and new design approaches are being developed to tackle them,” concludes Agarwala.
“The area of conducting hydrogels is still full of unresolved technological challenges, and thus provides researchers with opportunity for development, as this field is growing fast beyond its early stage. Improvement in the conductivity of the hydrogels may be one research direction, while incorporating new functionalities such as biodegradability and mechanical strength can open new avenues for applications. Innovation is also required in fabrication methods to allow varied composition of hydrogels to be laid down in desired fashion.”
What do you think of this news? Let us know your thoughts! Join the discussion of this and other 3D printing topics at 3DPrintBoard.com.[Source / Images: ‘Electrically Conducting Hydrogels for Health care: Concept, Fabrication Methods, and Applications’]
You May Also Like
NIST Grants $1.4 Million to America Makes for 3D Printed PPE
As the COVID-19 pandemic has swept the world and changed life as we know it in many ways—along with opening up many questions for the future—makers, researchers, and medical inventors...
French Army Deploys Massive Military Print Farm for Spare Parts
The French Army has recently partnered with HAVA3D, a prominent distributor and integrator of additive manufacturing solutions based out of Le Mans, France, to deploy one of the largest 3D...
The Value Proposition of 3D Printed Airplane Parts, via Stratasys Aerospace
In the wee hours of the morning of July 2, I attended the last segment of the Stratasys Aerospace Webinar Series, “Value Proposition of AM to Airlines,” enjoying a presentation...
SLA 3D Printing: Formlabs Offers Six New Resins for the Form 3, Form 3B & Form 2
Centered around the miracles of 3D printing, Formlabs tends to have the magic touch—whether individual users or companies are seeking new products like an SLA printer or choosing from a...
View our broad assortment of in house and third party products.