Srikkanth Balasubramanian, Marie-Eve Aubin-Tam, and Anne S. Meyer explore the idea of 3D printing with bacteria further in their recently published ‘3D Printing for the Fabrication of Biofilm-Based Functional Living Materials.’ With a focus on the power bacterial biofilms could have in a variety of applications, the researchers explain the benefits of these CD cell networks made up of proteins, lipids, polysaccharides, and nucleic acids.
As organic platforms for production and processing of biomaterials, the bacterial biofilms not only self-assemble and settle into spatial patterning, but they are also tough, demonstrating high mechanical stiffness, and resistance to high temperatures, antibiotics, pollutants, detergents, and more. The authors expect biofilms to be beneficial for applications like the following:
- Materials production
- Wastewater purification
Synthetic biology allows researchers to refine and strengthen the performance of ‘biofilm-forming bacteria,’ with the use of additional peptides and ‘genetically tractable bacteria’ like Escherichia coli and Bacillus subtilis in use for synthetic, engineered materials. In creating such biofilms, the following must be assessed:
- Determination of optimal peptide fusion sites
- Tolerance of fusion protein to mutations
- Toxicity of new peptide tags to the bacterial cells
- Functional assays for characterization of novel biofilm functionalities
“The resultant biofilm-derived materials can exhibit marked advantages over materials fabricated by planktonic bacteria cultures, in terms of their resistance to extreme and unexpected environments, reusability, spatial multiscale patterning, and tunable properties,” state the researchers.
There are challenges and concerns in using genetically modified bacteria, obvious, with the authors stating that 3D printed devices could then potentially be toxic and a hazard to humans—and the environment—should the bacteria be exposed.
“For societal applications such as drinking water plants, contamination risks could be eliminated by 3D printing cell-free functional extracellular matrix components that were isolated from biofilms by vacuum filtration. Such components will have longer stability and reusability compared to living bacteria and would not need constant maintenance,” concluded the researchers.
“Overall, the effectiveness, stability, and versatility of 3D bioprinting approaches in combination with the distinct characteristics of bacterial biofilms offer an ideal platform for the fabrication of biofilm-derived products in materials processing and manufacturing.”
You might be surprised to find out how often 3D printing and research regarding bacteria have been connected, from studies into stem-cell engineering to manufacturing living materials to fabricating cyanobacteria.
What do you think of this news? Let us know your thoughts! Join the discussion of this and other 3D printing topics at 3DPrintBoard.com.[Source / Images: ‘3D Printing for the Fabrication of Biofilm-Based Functional Living Materials’]
Subscribe to Our Email Newsletter
Stay up-to-date on all the latest news from the 3D printing industry and receive information and offers from third party vendors.
You May Also Like
Ricoh Partners with Materialise to Enhance 3D Printing in Hospitals
Ricoh (TYO: 7752) announced a partnership with Materialise (Nasdaq: MTLS) at the Radiological Society of North America (RSNA) 2023 event. This collaboration aims to make 3D printing more accessible and...
3D Printing Webinar and Event Roundup: November 26, 2023
Things are getting busy again in terms of 3D printing webinars and events! This week is the RSNA annual meeting, the World Manufacturing Forum, and more. HP is holding an...
3D Printing Financials: Stratasys Navigates Through Economic Uncertainty, Steady Profits and Revenue
Stratasys (Nasdaq: SSYS) unveiled its financial results for the third quarter of 2023, revealing a mixed scenario amid a backdrop of significant merger and acquisition (M&A) activities with Nano Dimension...
3D Printing News Briefs, November 18, 2023: Depowdering, Jewelry Patterns, & More
We’re kicking off 3D Printing News Briefs with a little business today, as Horizon Microtechnologies invested in a micro AM platform from Boston Micro Fabrication, and Rivelin Robotics announced a...
Upload your 3D Models and get them printed quickly and efficiently.