ROKIT Healthcare, in cooperation with a Massachusetts-based U.S. hospital, has completed pre-clinical studies for cartilage regeneration using the 3D bioprinting technology and is in the process of clinical studies with patients of age-related osteoarthritis in Egypt.
The pre-clinical study, performed together with the Charles Bragdon group at Massachusetts General Hospital, lasted about six months and followed up with the progress of hyaline cartilage regeneration in beagles.
Existing cartilage repair therapies, based on stem cell injections and seeding and culturing of cells onto alternative membranes, have limitations in treating cartilage which has complex 3D structures and compositions. Combining 3D bioprinting with optimized bioinks composed of minced cartilage and autologous solutions from the patient, ROKIT Healthcare seeks to offer a novel therapy that is founded on providing a stable environment for the recruitment of endogenous stem cells and the differentiation of 3D structurally positioned stem cells into chondrocytes in vivo.
“There has yet to be any truly regenerative method for cartilage repair despite osteoarthritis being one of the top public health burdens in this era of aging populations,” said Seok Hwan You, CEO of ROKIT Healthcare. ”Recently on the news there have been reports of recalls of artificial knee cartilage replacements, including products that have for long comprised the majority of cartilage repair markets. This testifies there are intrinsic limitations of synthetic and allogenic tissue engineering methods, and we need to find autologous alternatives that rely on bioprinting of autologous solutions to the defect site and creation of an endogenous regeneration niche. All of this needs to be done in the safest way that minimizes risk and long-term treatments.”
ROKIT Healthcare has completed applying for domestic and international patents for printing the cartilage regenerative 3D constructs using the MRI/CT scan data of the patient and inserting them back into the patient knee while minimizing the incision. Following the initial rounds of pre-clinical study in the U.S. and clinical study in Egypt, the clinical studies are planned to continue in Korea and Singapore.
Subscribe to Our Email Newsletter
Stay up-to-date on all the latest news from the 3D printing industry and recieve information and offers from thrid party vendors.
You May Also Like
3D Printing News Briefs, August 10, 2022: Events, Awards, & More
First up in today’s 3D Printing News Briefs is Formnext + PM South China, which returns to Shenzhen next month. Next, Lithoz won an award from Licensing Executive Society International....
Ganit Goldstein Uses Stratasys 3D Printing to Create Gorgeous GnoMon Fashion Collection
I’m always fascinated by MIT textile researcher and 3D designer Ganit Goldstein‘s work. Before completing her MA in Textiles at London’s Royal College of Art, she majored in fashion and...
3D Printed Space Habitat Now Open to Swiss Students to Live in
Our solar system has an incredible variety of worlds, and recent research has identified several off-Earth locations as potentially habitable for humans, like Mars, Europa, Enceladus, and the Moon. With...
Sakuu Opens Battery 3D Printing Facility in Silicon Valley
Silicon Valley startup Sakuu is using some of the funds from its total $62 million raised to open a new facility for its battery 3D printing platform. The multi-million-dollar site...