Some people are pros at swallowing pills, while others — between 40 and 50 percent, actually, according to surveys — really struggle with it, and dysphagia, or difficulty swallowing in general, is a common symptom in epileptic patients, particularly older patients. To make things worse, pills generally tend to get bigger as dosages increase, so patients with the most severe symptoms often end up with giant “horse pills” that are a challenge for anyone to swallow. So much of a challenge, in fact, that many people give up and stop taking their medication, leading to more seizures.
By 3D printing the SPRITAM tablets, Aprecia was able to make them porous, meaning that they instantly dissolve in a patient’s mouth with a sip of liquid. No more painful, stressful swallowing attempts, and no more missed doses — not for that reason, anyway.
“As we explored potential applications for our 3D printing technology in prescription drug products, it was important that we identified disease areas with a real need for patient-friendly forms of medication,” said Don Wetherhold, CEO of Aprecia. “SPRITAM is designed to transform what it is like to take epilepsy medication, and is the first in a line of products we are developing to provide patients and their caregivers with additional treatment options.”
SPRITAM is now available in four dose strengths: 250 mg, 500 mg, 750 mg and 1,000 mg. The pills do get bigger as the dose goes up, but that shouldn’t make a difference anymore, as they all dissolve instantly. Considering that over three million people in the United States are living with epilepsy, this could have a tremendous impact on treatment compliance and overall health. It will also likely open the door for Aprecia and other pharmaceutical companies to further develop other 3D printed drugs, and that’s definitely something to be excited about. Discuss in the 3D Printed SPRITAM forum over at 3DPB.com.