Exone end to end binder jetting service

UA Researchers Use 3D Printing to Help Fight Cancer

INTAMSYS industrial 3d printing

Share this Article

Medicine and 3D printing continue to merge with one another. We have seen numerous applications for 3D printing within the medical field, most centering around 3D bioprinting. Today the University of Alabama announced a unique combination of the 2 fields. The very first 3D printed model of a G-quadruplex DNA sequence, with its molecular structure, has been created.

g-quad1

3D Printed G-quadruplex Molecule

The work was done by Dr. Vincent F. Scalfini, the engineering and science librarian at UA, who teamed up with Dr. Stephen Neidle, and Stephan A. Ohnmacht, both working as researchers in the UK, at the University College London. The researchers converted x-ray crystallography data of the molecule, as well as the drug targeting it, into a 3D model, which they than manipulated in order to 3D print. The researchers feel that such technology will make major strides in the fight against cancer, as the 3D physical model will allow scientists to further understand the DNA sequence they are working with.

Dr. Scalfani explained the significance of his work as follows,
“Preparing the G-qaudruplex DNA sequence for 3D printing was a challenge and certainly pushed the limits of what we thought was possible in the UA 3D Lab. The structure is extremely intricate, containing multiple areas of stacked functional groups that are all surrounded by a common outer loop. The 3D printed G-quadruplex is stunning; you can see all of the symmetry, facets and angles within the molecule.”

It may seem rather useless to have a 3D printed physical representation of the DNA structure when researchers are able to view the same structure on a computer, however, those who see it that way, have never worked with this kind of data. The printed model is already being put to use in pre-clinical pancreatic cancer studies at the University, and will also give students at the school a hands on learning experience.

“G- quadruplex DNA is unusual as it is four-stranded, not two stranded like ‘normal’ double helical DNA we know,” Ohnmacht said.

For this very reason, having the means to handle the model, and truly understand it is invaluable to researchers. The ability for them to get a true feel for the three dimensional characteristics of the structure is priceless.

Discuss this story at 3DPrintBoard.

Share this Article


Recent News

$51M to Ramp up 6K’s Production of Batteries and 3D Printing Metals

Secret Audit Reveals US Military’s 3D Printing Tech Vulnerable to Cyberattacks



Categories

3D Design

3D Printed Art

3D Printed Food

3D Printed Guns


You May Also Like

3D Printing News Briefs, September 9, 2021: Events, Materials, & More

In today’s 3D Printing News Briefs, the first Formnext + PM South China finally opens this week. In materials news, a biomedical company introduced what it calls the first purified...

Featured

US Navy Issues $20M to Stratasys to Purchase Large-Format 3D Printers

The U.S. Navy has been steadily increasing its investment into practical 3D printer usage, as opposed to research. The latest comes in the form of a whopping $20 million contract...

3D Printing Webinar and Event Roundup: August 22, 2021

From food 3D printing and GE Additive’s Arcam EBM Spectra L 3D printer to 3D printing and CAD in a post-pandemic world and topology optimization, we’ve got a busy week...

Featured

The Largest 3D Printed Structure in North America: a Military Barracks in Texas

ICON’s latest 3D printed training barracks structure in Texas signals another positive step for the additive construction industry. Described by the company as the largest 3D printed structure in North...


Shop

View our broad assortment of in house and third party products.